The Natural Health Benefits of Rutin

Rutin is a bioflavonoid found in buckwheat, black tea, citrus fruits, and apple peels. The name comes from the herb rue, but it is actually a complex sugar found in foods.  In the 1940s, it was called vitamin P, even though it’s not a vitamin.  One of its main health roles is to help the body utilize Vitamin C more efficiently, as well as help produce collagen (the skin’s main building blocks). Rutin has long history of medicinal use - in fact, as of 2013 there are over 130 registered therapeutic medicinal preparations containing rutin in their formulations.

One key benefit of rutin is its ability to strengthen the lining of the blood vessels throughout the body to reduce bleeding and prevent them from collapsing.  One way it accomplishes this is through oxerutins, which are a group of flavonoid chemicals derived from naturally occurring rutin and which have been used in European supplements since the 1960s for treating and preventing varicose veins and leg ulcers.  According to University of Maryland Medical Center, “A number of studies have shown that flavonoids that come from rutin relieve swelling, aching, and pain from varicose veins.”  Because rutin strengthens arteries and veins, it is also used to help treat hemorrhoids, internal bleeding, and to help prevent hemorrhagic strokes.

Phi-Zymes from Baseline Nutritionals

What’s more, studies show that rutin may also be able to stop the formation of blood clots (thrombosis) altogether. This would be quite a health benefit, as thrombosis is one of the leading causes of death in the US. Not only can blood clots cause heart attacks and strokes, but deep venous thrombosis (DVT) and pulmonary embolisms as well.  Rutin is proving to be very effective with blood clots because it helps treat and prevent clots in both arteries and veins.  Clots in arteries are platelet-rich and clots in veins are fibrin-rich.  A study published in the Harvard Gazette suggests that this could be a safe alternative to aspirin, Plavix, and warfarin (Coumadin).  The authors add that even while on these drugs, each year there are approximately 400,000 recurrent episodes among patients who previously experienced a stroke or heart attack.  “Rutin proved to be the most potently anti-thrombotic compound that we ever tested,” said Robert Flaumenhaft, an investigator in the Division of Hemostasis and Thrombosis at BIDMC and associate professor of medicine at Harvard Medical School. This is one of the reasons you will find it in Jon Barron’s pHi-Zymes® formula.

In addition to these health benefits, rutin is also considered an antioxidant, meaning that it binds to free radicals in the body and neutralizes them. This ability to protect the body from disease as well as fight off any free radicals that accumulate offers other benefits as well. Since free radicals turn LDL cholesterol into plaques, blocking arteries and preventing normal blood flow (atherosclerosis), rutin may help reduce arterial blockage and high blood pressure, possibly decreasing the risk of heart disease and stroke.

Another new area of investigation for rutin is in treating osteoarthritis, a disease in which cartilage gradually wears away in the joints, making movement difficult and painful.  Scientists at the Nestle Research Center in Lausanne, Switzerland, found that rutin inhibited the enzyme Coll2-1, a marker for osteoarthritis.  Other research is being done to combine rutin with bromelain, a compound found in pineapples.  Since bromelain also reduces inflammation, combining the two is being considered as a powerful treatment for osteoarthritis.  Note that bromelain is also found in Jon Barron’s pHi-Zymes® formula.

Other benefits include:

  • Increases the elasticity of the arterial walls, which, in turn, promotes greater blood flow and improved vascular health.
  • Works as an anti-inflammatory.
  • Used to prevent a side effect of cancer treatment called mucositis (a painful condition marked by swelling and ulcer formation in the mouth or lining of the digestive tract).
  • Used to treat Meniere's disease (a condition that causes ringing in the ears, dizziness and intermittent hearing loss).
  • In combination with the proteins trypsin (which is also found in Jon Barron’s pHi-Zymes formula as part of the Fungal Pancreatin ingredient) and bromelain, rutin is also used to help treat osteoarthritis.

As mentioned before, rutin can be found in a number of fruits, vegetables, and plants but to get the true health benefits, it should never be taken with food.  This is why you will find it in Jon Barron’s pHi-Zymes® formula, which is also designed to be taken between meals, on an empty stomach.

Dosage: you can take up to 500 mg of rutin per day, or much higher for special circumstances.  There are no side effects, even when pregnant, but note that some antioxidants can interfere with chemotherapy or radiation for cancer.  If you choose to undergo these treatments for cancer, you need to talk to your doctor to see if you should avoid all antioxidant supplements during the weeks you take radiation or chemo or whether taking rutin would be advisable to prevent mucositis.  However, you can continue taking selected selected antioxidants after a treatment to help you recover from the side effects.




    Submitted by agirlwithoutaname on
    March 12, 2016 - 12:30am

    Jon, I love apples. I put 1/2 in my vegetable salad everyday. The unfortunate part is that I peel them so I can find all the 'bruises' and peel them away. Apples are terribly bruised these days. Some times I find that I've peeled 1/3 of an apple away to remove all the bruises. Are the bruises oxidized fruit? Fungus? Are they safe to eat?

    Submitted by BaselineFoundation on
    March 14, 2016 - 11:43am

    Impact to the fruit, which can happen during harvesting or transport or even when people in stores are picking it up and squeezing it can rupture cells near the surface of the fruit allowing oxygen to enter and turn the damaged areas brown. Although unattractive, it is perfectly safe to eat.

    Submitted by Eileen on
    April 7, 2017 - 5:38am
    Manchester ,

    Your article about Rutin is very interesting thanks.
    I recently watched a documentary about RLS (restless legs syndrome) from which I suffer. It highlighted the condition suffered by 4 individuals and the struggles they went through trying to cope with this condition. The doctor who commented on the condition said there was no treatment for RLS, but in my research about the condition, Rutin, as a supplement was recommended and I take it quite regularly for relief from my R LS. Within half an hour of taking it, the irritating sensation of spiders running up and down the inside of my calf muscles and feet clears completely, so I was surprised that the poor people on the documentary have never discovered it or been told about it.
    I hope this may help anybody who is suffering from RLS and not, as yet, heard of this wonderful natural remedy.

    Submitted by Debra on
    June 21, 2017 - 7:14pm
    Mount Isa ,

    My mother has always suffered with sore legs and now I've gotten a bit older I am the same. Mum suggested I try Rutin as it worked well for her, I did and it works well, I now make sure I always have them because without them my legs and hip start aching.

    Submitted by Haris Baki on
    June 29, 2017 - 5:02am
    İstanbul ,

    I suggest those who suffer from this ailments take rutin along with Daflon and Doxium (all trade mark pharmaceuticals worldwide) or their derivatives plus bromelain plus horse chestnut. Results are very satisfactory.

    Submitted by Karen on
    June 30, 2017 - 8:06am
    San Diego , California

    How do all these help? Do they compliment each other? Do you have side effects such as stomach upset or get dizzy after taking? (This happens to me if I take items on an empty stomach). Rutin said to take on an empty stomach. What are the other two for? Any info is appreciated. Thank you.

    Submitted by James Berardi on
    May 14, 2018 - 1:20pm
    New Market , Maryland

    Hello I am a young active male recently diagnosed with chronic venous insuffuciency in my deep veins. They would like me to take an aspirin everyday. Would rutin be a good susitute?

    Submitted by Paula on
    August 27, 2018 - 10:09am
    Sacramento , California

    Will a combination of Rutin and forskolin taken daily help lower my IOP. If so would results be permanent or temporary?

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