For those of you who don’t care about details and don’t want to ever read anything longer than a Tweet, let me summarize:
The coronavirus that currently has everyone freaked out is:
- Easily spread through person to person contact
- Has slightly better than a 2% mortality rate
- Kills primarily by initiating a cytokine storm or as a result of secondary pneumonia
- Is rapidly breaking containment
- There are ways to keep symptoms to a minimum and avoid complications that may lead to a bad end
The best defense is to maintain an optimized immune system AND make sure you have an adequate supply of natural anti-pathogens on hand. You won’t be able to prevent the virus if you’re exposed to it (this is a brand new virus, and no human being has any immunity to it), but it is possible to keep the viral load to a minimum so that it doesn’t progress into a cytokine storm, pneumonia, or acute respiratory distress syndrome (ARDS). If you do that, symptoms are likely to be mild.
But, for those of you who understand that knowledge is power, here’s the underlying story.
What Exactly is the Coronavirus?
Coronaviruses are not a single virus, but rather, a large family of viruses that mostly infect bats, pigs, and small mammals. However, a handful can infect humans and cause illness ranging from the common cold (about 20% of all colds are the result of coronaviruses) to more severe diseases such as SARS, MERS, and the new coronavirus. They are named for the crown-like spikes on their surface. And no, the fact that 20% of all colds are caused by a mere four of the many coronaviruses does not mean that the current coronavirus outbreak is nothing more than a common cold as some have proposed.1 Rush Limbaugh. “Overhyped Coronavirus Weaponized Against Trump. The Rush Limbaugh Show. Feb 24, 2020. (Accessed 25 Feb 2020.) https://www.rushlimbaugh.com/daily/2020/02/24/overhyped-coronavirus-weaponized-against-trump/ And even more confusingly, some of those same people have also theorized that it’s probably a “laboratory experiment that is in the process of being weaponized.” How it’s both a nothing-to-worry-about common cold AND a weaponized virus at the same time I’ll leave to brighter minds than mine to explain.
And speaking of conspiracy theories, over two dozen scientists, health experts and epidemiologists, in an open letter published in The Lancet, disputed Rush’s conspiracy theory that the virus is a bioweapon made in a lab near Wuhan.2 Charles Calisher, Dennis Carroll, Rita Colwell, et al. “Statement in support of the scientists, public health professionals, and medical professionals of China combatting COVID-19.” The Lancet. February 19,2020. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30418-9/fulltext And I quote, “We stand together to strongly condemn conspiracy theories suggesting that COVID-19 does not have a natural origin. Scientists from multiple countries have published and analyzed genomes of the causative agent…and they overwhelmingly conclude that this coronavirus originated in wildlife as have so many other emerging pathogens.” Yes, they could be lying or mistaken, but probably not.
Before COVID-19, only six coronaviruses had been known to be responsible for human diseases. Two are zoonoses (diseases which are transmitted to humans from animals). These would be SARS and MERS, both of which can be fatal. The remaining four viruses are widespread in human society, causing the common cold. COVID-19, the seventh such virus seems to borrow from both groups. It originally was a zoonotic disease, likely jumping from animals to humans in a Chinese Seafood Wholesale Market. Very quickly, it showed a facility to readily and rapidly spread from human to human, while still maintaining its zoonotic ability to kill people. The natural animal host of COVID-19 is undetermined, but the closest animal-coronavirus by genetic-sequence is a bat-coronavirus, and this is the likely ultimate origin of the virus,3 Chen Y, Liu Q, Guo D. “Emerging coronaviruses: genome structure, replication, and pathogenesis.” (2020) Journal of medical virology. https://pubmed.ncbi.nlm.nih.gov/31967327-emerging-coronaviruses-genome-structure-replication-and-pathogenesis/ , 4 Heymann DL, Shindo N. “COVID-19: What Is Next for Public Health?” (2020) Lancet. https://pubmed.ncbi.nlm.nih.gov/32061313-covid-19-what-is-next-for-public-health/ , 5 Ng LFP, Hiscox JA. “Coronaviruses in animals and humans.” (2020) BMJ (Clinical research ed.). 368: m634. https://pubmed.ncbi.nlm.nih.gov/32075782-coronaviruses-in-animals-and-humans/ although it seems the disease can also be transmitted by snakes.6 Yueying Pan, Hanxiong Guan, Shuchang Zhou, et al. “Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China.” (2020) European Radiology. https://pubmed.ncbi.nlm.nih.gov/32055945-initial-ct-findings-and-temporal-changes-in-patients-with-the-novel-coronavirus-pneumonia-2019-ncov-a-study-of-63-patients-in-wuhan-china/
So, this particular strain is brand new and has never previously been identified in humans, which again is why no human being on the planet has any immune system memory of it—and therefore no immunity. It was first named the 2019 novel coronavirus.7 Na Zhu, Dingyu Zhang, Wenling Wang, et al. “A Novel Coronavirus from Patients with Pneumonia in China, 2019.” (2020) New England Journal of Medicine. https://pubmed.ncbi.nlm.nih.gov/31978945-a-novel-coronavirus-from-patients-with-pneumonia-in-china-2019/ , 8 Perlman S. “Another Decade, Another Coronavirus.” N Engl J Med. 2020;382(8):760–762. https://pubmed.ncbi.nlm.nih.gov/31978944-another-decade-another-coronavirus/ It was then named COVID-19 by the World Health Organization (short for Corona Virus Disease, 2019). Around the same time, the Coronavirus Study Group of the International Committee on Taxonomy of Viruses named the virus SARS-CoV-2 (short for “Severe Acute Respiratory Syndrome coronavirus 2).9 Alexander E. Gorbalenya, Susan C. Baker, Ralph S. Baric, et al. “Severe acute respiratory syndrome-related coronavirus – The species and its viruses, a statement of the Coronavirus Study Group.” bioRxiv 2020.02.07.937862; https://www.biorxiv.org/content/10.1101/2020.02.07.937862v1 , 10 Enserink, M. (2020). “Update: ‘A bit chaotic.’ Christening of new coronavirus and its disease name create confusion.” Sciencemag.org. Feb. 12, 2020. (Accessed 25 Feb 2020.) In the end, COVID-19 seems to have won out.
The first cases were seen in the city of Wuhan, China in December 2019 (how far we have come in such a short time) and have been linked to the Huanan Seafood Wholesale Market.11 Na Zhu , 12 Perlman , 13 Hui DS, I Azhar E, Madani TA, et al. “The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health – The latest 2019 novel coronavirus outbreak in Wuhan, China.” Int J Infect Dis. 2020;91:264–266. https://pubmed.ncbi.nlm.nih.gov/31953166-the-continuing-2019-ncov-epidemic-threat-of-novel-coronaviruses-to-global-health-the-latest-2019-novel-coronavirus-outbreak-in-wuhan-china/ Person-to-person transmission readily occurs, and no effective treatment or vaccine currently exists.14 “Coronavirus Disease (COVID-19): Prevention & Treatment.” CDC February 15, 2020 (Accessed 27 Feb 2020.) https://www.cdc.gov/coronavirus/2019-ncov/about/prevention-treatment.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fcoronavirus%2Fabout%2Fprevention.html
Incidence and Distribution of the Virus
According to a Johns Hopkins online virus tracker, as of March 18, 2020, over 205,000 cases of COVID-19 have been confirmed worldwide, with the majority in China. However, Italy is also very high. (Sometimes the internet is astounding.)
On January 13, 2020, the first confirmed case outside China was diagnosed, a Chinese tourist in Thailand.15 Hui DS On 20 January, the first infected person in the United States was confirmed to be a man in the State of Washington who had recently returned from a visit to Wuhan.16 Holshue ML, DeBolt C, Lindquist S, et al. “First Case of 2019 Novel Coronavirus in the United States.” [published online ahead of print, 2020 Jan 31]. N Engl J Med. 2020;10.1056/NEJMoa2001191. https://pubmed.ncbi.nlm.nih.gov/32004427-first-case-of-2019-novel-coronavirus-in-the-united-states/ The disease has now been diagnosed in 33 territories, including Macau and Hong Kong, in five continents.17 Johns Hopkins , 18 Wang D, Hu B, Hu C, et al. “Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.” [published online ahead of print, 2020 Feb 7]. JAMA. 2020;10.1001/jama.2020.1585. https://pubmed.ncbi.nlm.nih.gov/32031570-clinical-characteristics-of-138-hospitalized-patients-with-2019-novel-coronavirus-infected-pneumonia-in-wuhan-china/
In the largest study to date, a paper published by the Chinese Center for Disease Control and Prevention (CCDC) analyzed all the cases diagnosed up to 11 February 2020, which came to 44,672 cases. Of these, 1.2% were asymptomatic and 80.9% were classed as “mild”. The overall mortality rate was found to be 2.3%.19 Perlman , 20 Johns Hopkins , 21 “Novel Coronavirus Pneumonia Emergency Response Epidemiology Team.” Zhonghua Liu Xing Bing Xue Za Zhi. 2020;41(2):145–151. https://pubmed.ncbi.nlm.nih.gov/32064853-the-epidemiological-characteristics-of-an-outbreak-of-2019-novel-coronavirus-diseases-covid-19-in-china/ Now, a 2.3% mortality rate doesn’t sound like a lot (just ask Rush Limbaugh), but it is. In fact, it’s huge. The Spanish Flu of 1919 had an almost identical mortality rate of 2.5%. The standard flu has a mortality rate of about 0.1% and that kills about 56,000 every year in the US (last year it was 80,000) and somewhere between 291,000 to 646,000 worldwide.22 “Seasonal flu death estimate increases worldwide.” CDC December 13, 2017. (Accessed 25 Feb 2020.) https://www.cdc.gov/media/releases/2017/p1213-flu-death-estimate.html Now here’s the fly in the ointment. Two percent may be small, but it’s 20 times bigger than 1/10 of one percent. Do the math (multiply the numbers above by 20) and you’re looking at the potential for some very large numbers. So yes, it’s “potentially” a big deal—although it’s highly unlikely to play out like that. More on that in a bit. (Note: ultimately, as more people are tested, the real mortality rate will probably end up somewhat less that 2.3%, but it is still likely to be several times higher than the numbers for seasonal flu.)
COVID-19 is primarily transmitted in a similar way to the common cold, that is face to face, either from sneezing/coughing or close contact with infected individuals’ bodily secretions.23 Heymann Think, family, friends, coworkers, buses, planes, trains, movie theaters, concerts, etc. Additionally, coronaviruses can survive for up to nine days on surfaces such as doorknobs and shopping cart handles.24 Rebecca Blankenship. “How long does coronavirus live on surfaces?” Medical News Bulletin. February 11, 2020. (Accessed 26 Feb 2020.) https://medicalnewsbulletin.com/how-long-does-coronavirus-live-on-surfaces/ Touch the surface anytime during those nine days and then touch your eyes, nose or mouth, and you have the possibility of infection. [Newer studies now say that COVID-19 lasts up to three days on surfaces and up to 30 minutes in the air when someone sneezes or coughs.]
The infection was declared a Public Health Emergency of International Concern (PHEIC) on 30 January 2020 by the WHO.25 “Statement on the second meeting of the International Health Regulations (2005) Emergency Committee regarding the outbreak of novel coronavirus (2019-nCoV)”. Who.int, 2020. https://www.who.int/news-room/detail/30-01-2020-statement-on-the-second-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-outbreak-of-novel-coronavirus-(2019-ncov)
Coronavirus: Initial Symptoms and Pathology
The evidence suggests that when COVID-19 enters the body—primarily through droplets in the air—it attaches to a particular receptor found in lung tissue.26 Zhao, Yu; Zhao, Zixian, Wang, Yujia, et al. “Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-nCov.” bioRxiv 2020.01.26.919985. https://www.biorxiv.org/content/10.1101/2020.01.26.919985v1.full From there, the virus “hijacks” the host cell’s mechanisms to make more copies of itself. Tissue damage happens as a result of viruses taking over the cell completely, causing it to die, or when immune cells mount a defense against the viral infection, leading to cell death.
If large numbers of cells die, then the affected organ—in this case, the lung— can’t function effectively.
Typically, coronaviruses in humans cause mild respiratory infections such as the common cold. COVID-19, on the other hand, has demonstrated an ability in some patients to go beyond mild symptoms and develop into ALI and ARDS, which is more typical of pneumonias. (Note: Acute lung injury (ALI) is a more recently coined term that includes ARDS but also milder degrees of lung injury.) ALI and ARDS always result from another severe underlying disease. ARDS is the acronym to remember, though, since it’s respiratory failure or cardio-respiratory issues resulting from ARDS that lead to patients dying.
Then again, some people can have the virus and yet present no symptoms while the virus is in incubation. Symptoms of COVID-19 may appear in as few as two days or take as long as 14 days after exposure to appear. And this part is particularly worrisome—the carriers of the virus are highly infectious even while demonstrating no symptoms of infection. Think millions of Typhoid Mary‘s walking around, completely asymptomatic, infecting everyone they come in contact with—even if just for a moment.
Some individuals, especially young children, may remain asymptomatic for the entire course of their illness. And many other individuals may demonstrate, at most, mild upper respiratory tract symptoms. Other symptoms can include fever, aches and pains, fatigue, chest pain, and a dry cough. All these people that we’ve just mentioned are the 98% who will survive COVID-19 illness without any problems. For a small handful, however, the course of the disease is quite different—fatal. In fact, there are two paths to death.
- Some people are young, with strong immune systems. For them, the problem is that the virus overstimulates their immune system, triggering a cytokine storm in which a person’s own immune system attacks the lungs, leading to a large release of fluid in the lungs (ARDS), eventually leading to that person “drowning” in their own lung fluids.
- The second group tends to be older, with weakened immune systems, and lungs already compromised by disease (think COPD and emphysema). For them, the virus can weaken the immune system even more, to the point that pneumonia takes hold. Severe pneumonia has multiple paths to death including ARDS, heart failure, and sepsis.
According to the Chinese Center for Disease Control, 81% of cases are mild, 14% are severe, and 5% are critical.27 The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. “Vital Surveillances: The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19.” China CDC Weekly. 2020, 2(8): 113-122. http://weekly.chinacdc.cn/en/article/id/e53946e2-c6c4-41e9-9a9b-fea8db1a8f51 And about half of those who go critical die.
Keeping in mind that patients can be infected for anywhere from two to 14 days before they exhibit symptoms (infecting everyone they meet the entire time), here’s how symptoms progress among typical patients once they first manifest:
- The first symptoms, if any, are likely to be a fever, fatigue, and myalgia (muscle pain)
- This might be followed by difficulty breathing, especially if the patient is older or has a preexisting condition.
- Most people start to feel better after about a week. But about 20% will elevate to either a cytokine storm or pneumonia, both of which can lead to Acute Respiratory Distress Syndrome and require hospital admittance. (And now let’s talk about ARDS.)
- The lungs are highly vascularized. There’s a lot of blood flow in the lungs, because that’s where carbon dioxide is removed from your blood and replaced by oxygen, which is required by every cell in your body. Normally, you want your airways to be relatively dry so that you can breathe in air from which the oxygen gets transferred to red bloods cells and carried to the rest of body. ARDS occurs when fluid leaks from small blood vessels and collects in the tiny air sacs in your lungs so they can’t fill with enough air. That build-up of fluid in the lungs is what can cause breathing distress, because now lungs aren’t exchanging carbon dioxide for oxygen very efficiently. In addition to your lungs being compromised, organs such as your kidneys or brain might begin to malfunction, or even shut down if they do not receive enough oxygen.
- ARDS/ALI typically occurs in people who are already critically ill or who have significant injuries. Severe shortness of breath—the main symptom of ARDS—usually develops within a few hours to a few days after the precipitating infection. But as we’ve seen with COVID-19, that timeframe can stretch out as long as two weeks.
- ARDS is characterized by an acute inflammatory response triggered by immune cells followed by a chronic fibroproliferative phase marked by progressive collagen deposition in the lung.28 Tisoncik JR, Korth MJ, Simmons CP, Farrar J, Martin TR, Katze MG. Into the eye of the cytokine storm. Microbiol Mol Biol Rev. 2012;76(1):16–32. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294426/ Pathogen-induced lung injury can progress into ALI or its more severe form, acute respiratory distress syndrome (ARDS), as was seen with SARS, more aggressive flu virus infections, and now COVID-19. Interlukin-1β is a key cytokine driving proinflammatory activity in bronchoalveolar fluid washing out of patients with lung injury.
- About 4% of all those infected will continue to worsen and require admittance to an ICU
- ARDS is usually treatable, and most people normally survive. But when the underlying trigger for the condition is strong enough, as with COVID-19, only about half of people who develop ARDS survive. The risk of death increases with age and the severity of illness. HOWEVER, sometimes people with strong immune systems also succumb. And the reason is that once a cytokine storm is unleashed, the stronger your immune system, the stronger the storm. In effect, young healthy people can die because their immune systems are so strong. (There is a way to mitigate this without compromising your immune system, and we will talk about why that’s not a good idea later.) Of the people who do survive ARDS, some recover completely while others experience lasting damage to their lungs.
- Over the next week of infection (from day 10-17) about half of those admitted to ICU will recover. The other half will not.
Treatment and Prognosis
Currently, no specific treatment or vaccine exists for COVID-19, which is why most efforts have been made to contain the virus and prevent infected people from spreading the disease. This includes personal hygiene, fitted masks, and the avoidance of large crowds and crowded environments.29 Chen
In healthcare facilities, it is crucial to diagnose COVID-19 as rapidly as possible, quarantine infected cases, and provide effective supportive therapies including antibiotics, antivirals, steroids and supportive measures. Oxygen and the use of a ventilator have also been used when necessary.
While no specific antiviral therapies for COVID-19 currently exist, the combination of the protease inhibitors ritonavir and lopinavir (or a triple combination of these antiviral agents with the addition of ribavirin) showed some success in the treatment of SARS,30 Zhang L, Liu Y. “Potential Interventions for Novel Coronavirus in China: A Systematic Review [published online ahead of print, 2020 Feb 13].” J Med Virol. 2020;10.1002/jmv.25707. https://pubmed.ncbi.nlm.nih.gov/32052466-potential-interventions-for-novel-coronavirus-in-china-a-systematic-review/ and early reports suggest similar efficacy in the treatment of COVID-19.31 Lim J, Jeon S, Shin HY, et al. “Case of the Index Patient Who Caused Tertiary Transmission of COVID-19 Infection in Korea: the Application of Lopinavir/Ritonavir for the Treatment of COVID-19 Infected Pneumonia Monitored by Quantitative RT-PCR.” J Korean Med Sci. 2020;35(6):e79. Published 2020 Feb 17. https://pubmed.ncbi.nlm.nih.gov/32056407-case-of-the-index-patient-who-caused-tertiary-transmission-of-covid-19-infection-in-korea-the-application-of-lopinavirritonavir-for-the-treatment-of-covid-19-infected-pneumonia-monitored-by-quantitative-rt-pcr/
Vaccines for the coronaviruses have been under development since the SARS outbreak, but none are yet available for human patients.32 Chen , 33 Ng LFP A phase I trial in humans of a potential vaccine against MERS-CoV has already been performed in the UK.34 Ng LFP It is possible that an effective MERS vaccine might also have some applicability to COVID-19, but that’s purely speculative at the moment.
The key to the higher mortality rate for COVID-19 is the cytokine storm. A cytokine storm is triggered when the body perceives that a viral attack is more than it can handle through a normal response. This can happen in several different ways.
- A virus can be so virulent that its assault on the body is so great it triggers a cytokine storm. A normal immune system protects against invaders, but an immune system driven into over-active by an aggressive virus can not only damage the lungs but also other organs, including the kidneys, liver and heart.
- A virus can be so new (unlike most flus or colds) that the body has no memory of it, or any virus like it. This means your immune system can’t rely on its best, most trained defenders, the B-Cells and especially the T-Cells. Instead, it must turn to the extremely aggressive, but untrained, shock troops of the immune system, the macrophages and dendritic cells. They are powerful; they are quick; and they are aggressive. But being untrained, their attack may not be so precise. In other words, they can cause collateral damage. This is the pathway that can lead healthy, young people into the critical stages of illness.
- A virus by itself may not be strong enough to trigger a cytokine storm, but it may trigger a secondary infection (usually pneumonia) which, when combined with the initial infection, produces enough viral overload to trigger a cytokine storm. Any respiratory virus, including flu, respiratory syncytial virus, human metapneumovirus, and now COVID-19 can lead to pneumonia. This is how seasonal flu kills over 600,000 people a year. People don’t die from the flu, they die from the storm unleashed by the pneumonia, which was brought on as a secondary infection. Seniors with weakened immune systems are particular vulnerable to this pathway if they are infected with COVID-19, and the majority of deaths so far have come through this scenario—mostly involving older men.
However the storm is triggered, it causes your immune system to go nuts, whipping itself into a frenzy in response to the invading virus/viruses. A biochemical cascade of immune cells and immune system bio-chemicals such as interferon, interleukin, and monokines—collectively known as cytokines—literally pours into the lungs bringing macrophages and dendritic cells along with them. The subsequent damage to the lung tissue caused by these cells and biochemicals leads to ARDS that can literally chew up a person’s lung tissue, causing fluid to pour into the lungs, ultimately causing the victim to suffocate as a result of their own disease-fighting chemistry. The patient literally drowns in their own body fluids.
Most common flu’s do not produce cytokine storms. Most flu’s that kill people usually do so to those who have weak immune systems by eventually opening the door for pneumonia, which subsequently triggers a cytokine storm. That’s why health authorities specify that the very old and the very young are prime candidates for annual flu vaccines (even though they don’t work very well). But swine flu, avian flu, the great flu pandemic of 1918, and now COVID-19 are different animals. Yes, they can follow the same path in seniors with weakened immune systems. But because they are so virulent, and because human immune systems have no memory of them, they don’t need pneumonia to kill you. They can kill you by directly unleashing a cytokine storm, which means that it is your own, healthy immune system that kills you. And this means that although the most vulnerable are the very old (especially those with weak immune systems and/or underlying health conditions), healthy adults and pregnant women and people who have very strong immune systems are not free of risk, even if that risk is low. Curiously, at least to this point, young children do not seem to be particularly vulnerable.
To translate that into English, in a cytokine storm, the immune system overacts to the invasion of pathogens, and it’s the immune system itself that damages the lungs, not the virus. Think of it like using a sandblaster to scratch an itch instead of your finger. There’s going to be collateral damage. It’s the cytokine storm that made both SARS and MERS, along with the bird flu, so deadly. An important difference between those infections and COVID-19, though, is that almost all infections with those diseases were from animal to human. Human to human infection, when it occurred, was both rare and difficult. What sets COVID-19 apart is how easily it transmits between humans. Add in the fact that humans can be highly infectious for up to two weeks without displaying a single symptom, and you have a concerning situation.
Looking to the Future
On Friday, Feb 21st, the World Health Organization director general, Tedros Adhanom Ghebreyesus, said that there was still a chance to contain the virus, “but the window of opportunity is narrowing.” Just four days later, that optimistic projection was fading. On Tuesday, Feb 25th, American health authorities said they ultimately expect the virus to spread throughout the United States and are urging local governments, businesses, and schools to develop plans like canceling mass gatherings or switching to teleworking. As Dr. Nancy Messonnier, a senior official with the CDC said in a telebriefing, “Ultimately, we expect we will see community spread in this country. It’s not so much a question of if this will happen anymore but rather more a question of exactly when this will happen and how many people in this country will have severe illness.”35 “Transcript for the CDC Telebriefing Update on COVID-19.” CDC February 26, 2020. https://www.cdc.gov/media/releases/2020/t0225-cdc-telebriefing-covid-19.html Messonnier went on to say: “We are asking the American public to prepare for the expectation that this might be bad.” And finally, she pointed out, there are concerns that the outbreak poses a threat to the security of the US drug supply chain because a high proportion of ingredients used to make medicine is made in China, where the virus is causing massive disruption.
The headline in an article in The Atlantic says it all: “You’re Likely to Get the Coronavirus.”36 James Hamblin. “You’re Likely to Get the Coronavirus.” The Atlantic. February 24, 2020. (Accessed 26 Feb 2020.) https://www.theatlantic.com/health/archive/2020/02/covid-vaccine/607000/ In the article, James Hamblin writes:
“The Harvard epidemiology professor Marc Lipsitch is exacting in his diction, even for an epidemiologist. Twice in our conversation he started to say something, then paused and said, ‘Actually, let me start again.’ So, it’s striking when one of the points he wanted to get exactly right was this: ‘I think the likely outcome is that it will ultimately not be containable.’
“Lipsitch predicts that within the coming year, some 40 to 70 percent of people around the world will be infected with the virus that causes COVID-19. But, he clarifies emphatically, this does not mean that all will have severe illnesses. “It’s likely that many will have mild disease, or may be asymptomatic,” he said. As with influenza, which is often life-threatening to people with chronic health conditions and of older age, most cases pass without medical care.”
And that, of course, is precisely why COVID-19 is likely to be unstoppable. Viruses like SARS, MERS, and the bird flu were eventually contained in part because:
- They weren’t infectious before symptoms appeared.
- They were more intense and had a higher fatality rate. In other words, once you had symptoms, you were too sick to be out and about and mingling with people.
- And if you were going to die, you tended to die pretty quickly.
But because the current coronavirus can be asymptomatic, or at least very mild, there’s a better chance people will be going about their day as normal unknowingly spreading infection. Additionally, because people won’t know when they started spreading infection, it will be that much harder to trace and prevent the disease from spreading to others.
The Atlantic reports Lipsitch is definitely not alone in his prediction. There’s an emerging consensus that the outbreak will eventually morph into a new seasonal disease, which, per The Atlantic, could one day turn “cold and flu season” into “cold and flu and COVID-19 season.”
And one final reminder. Although Professor Lipsitch said “it’s likely that many will have mild disease,” that also means that some will not. And a small percentage applied to 40 to 70 percent of the world’s population is a very, very large number.
Now let’s talk about you can avoid being one of them.
What to Do? What to Do? What to Do?
- First of all, reassurances from government officials that COVID-19 is not going to hit the United States are nonsense, but don’t panic. Despite the fact that it looks like this virus is going to spread far and wide, for “most” people, symptoms will be mild or even non-existent. But also understand that, as I just mentioned, small percentages of people being critically ill and dying works out to be very large numbers if applied across enough people.
- Look to the future. Time is your best friend. The longer you can go without getting infected, the better your chances will be of never getting infected or surviving any infection you do get. As the pool of “once infected people” grows, the ability of the virus to spread diminishes. In other words, your chances of getting COVID-19 will follow a bell curve. For the next 12 months or so, they will increase dramatically, and then begin to fade—eventually getting very low. (Note: there may be a slow down to the curve as warmer months appear since early evidence indicates that, like the flu virus, COVID-19 thrives in cold, dry weather VS hot, moist weather. If so, things will accelerate again as the colder fall months arrive.)
- Also, over time, medical researchers will develop proven treatments that go far beyond mere palliative care. It’s worth noting—for those of you who have not been paying attention—that even Ebola is no longer incurable. Recently, Ebola treatments have been successful 90 percent of the time when symptoms were detected early.
- Speaking of which, an alternative that might speed things up is that, instead of creating brand new drugs to combat COVID-19, researchers are looking at the possibility of repurposing already existing drugs. For example, researchers have found that both remdesivir (one of the drugs currently be used to combat Ebola in Africa) and chloroquine (a widely used and FDA approved anti-malarial and autoimmune disease drug) were both effective in stopping COVID-19 from replicating in a lab dish. 37 Wang, M., Cao, R., Zhang, L. et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res (2020). https://doi.org/10.1038/s41422-020-0282-0 Also, both drugs were effective at low concentrations, and neither drug is considered particularly toxic to human cells. But fully testing both drugs on humans for use against COVID-19 and gearing up production for these drugs to be used on a massive scale will still take time, and the coronavirus is spreading at exponential speed. Also, it probably—and unfortunately—should be mentioned that if it’s decided to use these drugs for COVID-19, they will simply shift supplies currently being used in Africa to fight Ebola and malaria, to more politically “favorable” locations in the world, at least until production ramps up.
- And keep in mind that, given enough time, a vaccine will be developed. For example, and most people are not aware of this, the newly developed Ebola vaccine is proving highly effective in preventing at-risk people in the Democratic Republic of Congo from becoming infected. As for COVID-19, researchers are already working on a vaccine based on the one used for Ebola. Claims by some in the government that it is nearly finished are, at best, wishful thinking. However, within the next 24 months, we are likely to see a vaccine that is at least “mostly” effective and with “minimal” side effects.
- And if you want to be proactive, use natural immune boosters to keep your immune system optimized. Yes, under one set of circumstances, a strong immune system increases the risk of a cytokine storm. But under most scenarios, having a strong immune system will hold the viral level down enough so that you can’t develop a cytokine storm. Remember, although some healthy people are getting critically ill, the vast majority of those suffering from acute symptoms and dying are those with compromised immune systems.
- But most important of all, keep a supply of natural antipathogens on hand and begin taking them hard and strong at the first sign of symptoms, or if you believe you have been in contact with an infected person. Again, it’s not about curing the disease. All you need to do is support your body’s ability to hold the viral load down low enough so that you never develop pneumonia, or your immune system never kicks into a cytokine storm followed by ARDS. The bottom line is that if you prevent COVID-19 from initiating a cytokine storm, its symptoms are pretty mild for most people–much less than the flu or even most colds. Do that; keep the viral load down, and you can be like Mad Magazine’s Alfred E. Newman. “What, me worry?”
PS: Many people use elderberry extract for dealing with the flu, but it should be noted that it does so, as do many immune boosters, by increasing the cytokine response,38 Barak V, Halperin T, Kalickman I. “The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines.” Eur Cytokine Netw. 2001;12(2):290–296. https://pubmed.ncbi.nlm.nih.gov/11399518-the-effect-of-sambucol-a-black-elderberry-based-natural-product-on-the-production-of-human-cytokines-i-inflammatory-cytokines/ which means you probably want to use it in concert with natural antipathogens.
Editor’s Note: On 3/12/20, Jon posted a follow up to this newsletter answering all the questions that arose in the days since this newsletter was first released: COVID-19: There’s No Need for Panic
|↑1||Rush Limbaugh. “Overhyped Coronavirus Weaponized Against Trump. The Rush Limbaugh Show. Feb 24, 2020. (Accessed 25 Feb 2020.) https://www.rushlimbaugh.com/daily/2020/02/24/overhyped-coronavirus-weaponized-against-trump/|
|↑2||Charles Calisher, Dennis Carroll, Rita Colwell, et al. “Statement in support of the scientists, public health professionals, and medical professionals of China combatting COVID-19.” The Lancet. February 19,2020. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30418-9/fulltext|
|↑3||Chen Y, Liu Q, Guo D. “Emerging coronaviruses: genome structure, replication, and pathogenesis.” (2020) Journal of medical virology. https://pubmed.ncbi.nlm.nih.gov/31967327-emerging-coronaviruses-genome-structure-replication-and-pathogenesis/|
|↑4||Heymann DL, Shindo N. “COVID-19: What Is Next for Public Health?” (2020) Lancet. https://pubmed.ncbi.nlm.nih.gov/32061313-covid-19-what-is-next-for-public-health/|
|↑5||Ng LFP, Hiscox JA. “Coronaviruses in animals and humans.” (2020) BMJ (Clinical research ed.). 368: m634. https://pubmed.ncbi.nlm.nih.gov/32075782-coronaviruses-in-animals-and-humans/|
|↑6||Yueying Pan, Hanxiong Guan, Shuchang Zhou, et al. “Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China.” (2020) European Radiology. https://pubmed.ncbi.nlm.nih.gov/32055945-initial-ct-findings-and-temporal-changes-in-patients-with-the-novel-coronavirus-pneumonia-2019-ncov-a-study-of-63-patients-in-wuhan-china/|
|↑7||Na Zhu, Dingyu Zhang, Wenling Wang, et al. “A Novel Coronavirus from Patients with Pneumonia in China, 2019.” (2020) New England Journal of Medicine. https://pubmed.ncbi.nlm.nih.gov/31978945-a-novel-coronavirus-from-patients-with-pneumonia-in-china-2019/|
|↑8||Perlman S. “Another Decade, Another Coronavirus.” N Engl J Med. 2020;382(8):760–762. https://pubmed.ncbi.nlm.nih.gov/31978944-another-decade-another-coronavirus/|
|↑9||Alexander E. Gorbalenya, Susan C. Baker, Ralph S. Baric, et al. “Severe acute respiratory syndrome-related coronavirus – The species and its viruses, a statement of the Coronavirus Study Group.” bioRxiv 2020.02.07.937862; https://www.biorxiv.org/content/10.1101/2020.02.07.937862v1|
|↑10||Enserink, M. (2020). “Update: ‘A bit chaotic.’ Christening of new coronavirus and its disease name create confusion.” Sciencemag.org. Feb. 12, 2020. (Accessed 25 Feb 2020.)|
|↑13||Hui DS, I Azhar E, Madani TA, et al. “The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health – The latest 2019 novel coronavirus outbreak in Wuhan, China.” Int J Infect Dis. 2020;91:264–266. https://pubmed.ncbi.nlm.nih.gov/31953166-the-continuing-2019-ncov-epidemic-threat-of-novel-coronaviruses-to-global-health-the-latest-2019-novel-coronavirus-outbreak-in-wuhan-china/|
|↑14||“Coronavirus Disease (COVID-19): Prevention & Treatment.” CDC February 15, 2020 (Accessed 27 Feb 2020.) https://www.cdc.gov/coronavirus/2019-ncov/about/prevention-treatment.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fcoronavirus%2Fabout%2Fprevention.html|
|↑16||Holshue ML, DeBolt C, Lindquist S, et al. “First Case of 2019 Novel Coronavirus in the United States.” [published online ahead of print, 2020 Jan 31]. N Engl J Med. 2020;10.1056/NEJMoa2001191. https://pubmed.ncbi.nlm.nih.gov/32004427-first-case-of-2019-novel-coronavirus-in-the-united-states/|
|↑17, ↑20||Johns Hopkins|
|↑18||Wang D, Hu B, Hu C, et al. “Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.” [published online ahead of print, 2020 Feb 7]. JAMA. 2020;10.1001/jama.2020.1585. https://pubmed.ncbi.nlm.nih.gov/32031570-clinical-characteristics-of-138-hospitalized-patients-with-2019-novel-coronavirus-infected-pneumonia-in-wuhan-china/|
|↑21||“Novel Coronavirus Pneumonia Emergency Response Epidemiology Team.” Zhonghua Liu Xing Bing Xue Za Zhi. 2020;41(2):145–151. https://pubmed.ncbi.nlm.nih.gov/32064853-the-epidemiological-characteristics-of-an-outbreak-of-2019-novel-coronavirus-diseases-covid-19-in-china/|
|↑22||“Seasonal flu death estimate increases worldwide.” CDC December 13, 2017. (Accessed 25 Feb 2020.) https://www.cdc.gov/media/releases/2017/p1213-flu-death-estimate.html|
|↑24||Rebecca Blankenship. “How long does coronavirus live on surfaces?” Medical News Bulletin. February 11, 2020. (Accessed 26 Feb 2020.) https://medicalnewsbulletin.com/how-long-does-coronavirus-live-on-surfaces/|
|↑25||“Statement on the second meeting of the International Health Regulations (2005) Emergency Committee regarding the outbreak of novel coronavirus (2019-nCoV)”. Who.int, 2020. https://www.who.int/news-room/detail/30-01-2020-statement-on-the-second-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-outbreak-of-novel-coronavirus-(2019-ncov)|
|↑26||Zhao, Yu; Zhao, Zixian, Wang, Yujia, et al. “Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-nCov.” bioRxiv 2020.01.26.919985. https://www.biorxiv.org/content/10.1101/2020.01.26.919985v1.full|
|↑27||The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. “Vital Surveillances: The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19.” China CDC Weekly. 2020, 2(8): 113-122. http://weekly.chinacdc.cn/en/article/id/e53946e2-c6c4-41e9-9a9b-fea8db1a8f51|
|↑28||Tisoncik JR, Korth MJ, Simmons CP, Farrar J, Martin TR, Katze MG. Into the eye of the cytokine storm. Microbiol Mol Biol Rev. 2012;76(1):16–32. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294426/|
|↑30||Zhang L, Liu Y. “Potential Interventions for Novel Coronavirus in China: A Systematic Review [published online ahead of print, 2020 Feb 13].” J Med Virol. 2020;10.1002/jmv.25707. https://pubmed.ncbi.nlm.nih.gov/32052466-potential-interventions-for-novel-coronavirus-in-china-a-systematic-review/|
|↑31||Lim J, Jeon S, Shin HY, et al. “Case of the Index Patient Who Caused Tertiary Transmission of COVID-19 Infection in Korea: the Application of Lopinavir/Ritonavir for the Treatment of COVID-19 Infected Pneumonia Monitored by Quantitative RT-PCR.” J Korean Med Sci. 2020;35(6):e79. Published 2020 Feb 17. https://pubmed.ncbi.nlm.nih.gov/32056407-case-of-the-index-patient-who-caused-tertiary-transmission-of-covid-19-infection-in-korea-the-application-of-lopinavirritonavir-for-the-treatment-of-covid-19-infected-pneumonia-monitored-by-quantitative-rt-pcr/|
|↑33, ↑34||Ng LFP|
|↑35||“Transcript for the CDC Telebriefing Update on COVID-19.” CDC February 26, 2020. https://www.cdc.gov/media/releases/2020/t0225-cdc-telebriefing-covid-19.html|
|↑36||James Hamblin. “You’re Likely to Get the Coronavirus.” The Atlantic. February 24, 2020. (Accessed 26 Feb 2020.) https://www.theatlantic.com/health/archive/2020/02/covid-vaccine/607000/|
|↑37||Wang, M., Cao, R., Zhang, L. et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res (2020). https://doi.org/10.1038/s41422-020-0282-0|
|↑38||Barak V, Halperin T, Kalickman I. “The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines.” Eur Cytokine Netw. 2001;12(2):290–296. https://pubmed.ncbi.nlm.nih.gov/11399518-the-effect-of-sambucol-a-black-elderberry-based-natural-product-on-the-production-of-human-cytokines-i-inflammatory-cytokines/|
Thanks for the article. You say that we should keep anti-pathogens on hand, and begin taking them hard and strong at the first signs of illness, but you didn’t suggest what natural anti pathogens to have and use. Will you please suggest some, that the average person can both locate and afford? Thank you.
There are three reasons we do not mention a product by name.
—The FDA does not take kindly to anyone making medical claims for anything other than prescription drug. The article, therefore, does not pitch a particular product.
—The Baseline of Health Foundation is not a commercial site. Its purpose is to provide information. It doesn’t sell product. Baseline Nutitionals, however, the company that carries Jon Barron’s formulas does sell product. And since it provides funding for the Foundation, they get to do make small announcements on the Foundation website site and in our mailings.
—Jon’s ultimate purpose in anything he writes (and for the Foundation itself, in fact) is to arm you with information so that you can make intelligent decisions about your own health choices. It is not his or our intent to pressure you into buying any particular formula, even Jon’s. we do admit that sometimes that line gets crossed because it’s very hard to separate what Jon knows from what we do, but that is our intent.
That said, there is an announcement for Baseline Nutritionals in the middle of the newsletter that does point to the antipathogenic formula Jon created to address infectious situations. It is modeled after the great herbalist John Christopher’s Anti-plague Formula (which should provide a hint as to its purpose) but has been significantly updated.
I read the ‘Using Natural Anti-Pathogens’ article as well. Would liposomal vitamin C (or even IV vit C) be good to have on hand as well during the incubation or full blown infection? Attaching article I found for reference: http://orthomolecular.org/resources/omns/v16n07.shtml
Vitamin C would certainly be useful for helping build your immune system and for helping control free radicals, although a full-spectrum antioxidant would likely be more helpful in that regard. However, the amount of vitamin C required to have an antiviral effect requires intravenous, not oral administration. Using an antipathogenic formula is a much easier and more effective way to go in that regard.
Chris Masterjohn has stated that we SHOULD use Elderberry and STOP using large amounts of Vitamin C, D and A. Who really knows? No one knows.
According to these guys, what a person should take for this virus depends on whether they’re taking it prophylactically, during an initial infection in the acute stage, or after the virus has advanced into the chronic stage. Just FYI for consideration.
Immune System and Coronavirus, Dr. Guillermo Ruiz and Ari Whitten
There are other Coronavirus-related interviews on the same YouTube channel and blog, as well as the following:
Dr. Andrew Kaufman on COVID-19 being a lung Exosome
Herbal Treatment For Coronavirus Infections
Hydroxychloroquine and Azithromycin as a Treatment of COVID-19: Results of an Open-Label Non-Randomized Clinical Trial
Your First Line of Defense Against Viral Infections
Fighting Viruses, and Winning; From the Flu to Bio Terrorism.
I know it’s a lot, but if we overlay different sources (that are citing the same sources), perhaps we will see some commonalities arise.
Stay safe and be well,
I would love to hear a response to Margaret’s question above. Chris Masterjohn and most online holistic MDs advocate the use of elderberry, and seemingly all but Masterjohn advocate high dose Vitamins C & D. Please let us know your thoughts on that. Thank you!
We responded to the question about Vitamin C above. Hope that helps.
CoronaVirus: prevention, nursing and treatment
(Details of action of remedies explained)
The following are the remedies against fever, sore throat,
lethargy, runny nose, productive cough etc. and they can work as
preventive also against pneumonia. Mind it, I have prescribed the
remedies keeping in view only the symptoms of novel Corona Virus
COVID-19. Therefore, they are bound to provide relief.
Homeopathic remedies seldom fail if correctly selected and
1) Aconite Napellus 30 (for fever)
2) Bryonia alba 30 (for stictching pain and coryza)
3) Rhus Toxicodendron 30 (sneezing and sore throat)
4) Arsenic Album 30 (exhaustion, restlessness and cold prevention)
5) Lemna Minor 200 ( a catarrhal remedy)
6) Kali Bichromicum 200 (it soothes all mucus membrane)
1) Mercurius Solubilis 200 ( for body’s sensitiveness to cold and soreness))
2) Sulphur 30 (pressure of dry cough/productive cough on throat)
3) Pyrogenium 30 (to terminate any infection viral/bacterial)
4) Nitricum Acidum 200 (any kind of ulcer, stitching pain etc.)
5) Belladonna 30 (nausea, vomiting, fever etc.)
6) Mercurious biniodtus 200 (throat infection of any kind)
1) Stigmata Maydis Q (it’s action is diuretic)
1) Echinacea angustifolia Q (on any kind of infection, it acts wonderful)
1) Hydrastis Canadensis Q (mucus membrane, liver and anorexia)
1) Baryta Iodata 3X, 2X or 1X, if available, 1X will be more
effective. (high immune booster, its action is on WBC)
1) Naja Tripudians 30 (it stimulates heart including effective valvular disease)
1) Bryonia alba 30 (for chest pain and for drying the mucus)
2) Phosphorus 30 (any infection in chest, it prevents any lung’s bleeding)
3) Ferrum Phosphoricum 30 (any inflammation, catarrhal affections of respiratory tract)
1) Mephites 3X (any dry, suffocative, spasmodic cough)
1) Oxydendron Q (a remedy for dropsy and anasarca, cystitis etc.)
These are the remedies for corona virus infection selected
by me for the time being. How to prescribe?
At first procure all these medicines in liquid form in equal
quantity. Then prepare mixture of medicines mentioned under (A) and
(B), in two separate sterilized bottles pouring all the medicines in
equal quantity according to their names. In Bottle “A” six remedies
and in “B” six remedies have to be poured as mentioned above under
the respective groups, then shake both the bottles vigorously for two
minutes, and the mixtures are ready for use. (A) is to be started
quickly as soon as minor viral symptoms appear taking five-drop for a
dose in one teaspoonful of water every fifteen minutes or early until
improvement sets in, then later at long interval of say half an hour.
If there is serious bouts of fever as well as severe productive cough,
then mixture (B) has to be started simultaneously in five-drop a dose
in a teaspoonful of water. It will quickly arrest the productive cough
and fever and provide strength to the respiratory tract. How to take
both the remedies together? Take at first (A), and after five minutes
take (B). Then wait for ten minutes and take again (A) and followed
by (B), When improvement sets in, slowly increase the time gap.
Within five to six days, a patient will begin to feel full strength
and asymptomatic, and then the patient can be released with an
instruction to continue taking medicines at least for further two
weeks say six times a day. Minor infections will be
relieved simply within a few hours with only (A). Nobody will believe
simply administration of two to three doses will arrest the initial
symptoms. Yes, one can go for blood test also simultaneously to be
more sanguine against any infection.
In the mean while routine blood test has to be conducted including
platelets and RBC and WBC. (TC DC Hemoglobin and ESR). If WBC
count displays less than 6800, then (F) Baryta Iodata 3X: usually this is
available, and give it to the patient two grams thrice a day (because
I have marked the Corona Virus does not allow time) to raise the
WBC count to minimum 6800. My experience says that if WBC count
falls below 6800 even slightly the body fails to resist infection and viral
infection quickly passes into the lungs, otherwise simply touching the
patient like with runny nose and causing little irritation in throat
and slight fever the infection will pass off without doing any major
harm. Please don’t express hundred percent confidence in the version
of any medical textbook, practical experience is more important. If
WBC reading remains in between 6800 and 9000, then the patient
remains fine, if more than 9000 the patient begins to feel feverish or
if it is less than 6800 any person becomes prone to quick infection. In
this case any simple cold symptoms may trigger cough by passing
the infections into the lungs. All medical textbooks version I think is
wrong in terms of reading the blood count.
If UTI or any other infection sets in or abnormal rise in
Neutrophil/Eosinophil is detected then (D) has to be started three
hourly (minimum four times a day), taking ten-drop in a half cup of
water for a dose. (D) Echinacea Q can also be prescribed if WBC
count goes beyond 9000 count. Echinacea Q can work wonder in
any acute infection. If diarrhea, give 15 drops of (E) in 1/4th cup
of water at an interval of 15 minutes. With three doses, the
diarrheal tendency will be completely arrested, and the patient
begins to feel good appetite, if dysentery, then mix up both (D) ten
drops and (E) Hydrastis Canadensis Q fifteen drops in half a cup
of water half hourly and four to five doses dysentery symptom
will be arrested.(E) is also a good liver remedy. For any liver
problem or loss of appetite or anorexia, five drops of
(E) Hydrastis Can Q three times in little water a day
is enough. It kills intestinal worms also.
Prevention, and diagnosis, how?
There are lots of talks about asymptomatic infection of corona virus, I
don’t think there is much logic in such arguments. This happens, because
most of the doctors have lost their clinical eyes these days and simply rely
on the findings of machines, which is wrong. Seldom does a doctor feel
the pulse of a patient, his examination is cursory, which is also wrong! Every
patient as soon as is infected by any viral infection within hours begin to feel
exhausted, though he may not be having oral temperature more than 98.6*F.
Perhaps most of the doctors do not know; keep aside the textbook theory of
normal body temperature, if taken orally, is only 97.5*F, beyond that the
the body begins to feel simply lethargic and pulse also becomes slightly
more than 80. Please do not laugh at my conclusion, this is my experience
of more than thirty years. To manifest full symptoms, it may take days. But
within this period the patient may infect hundreds of other people. Now, if
we really want to prevent further spread of infection, then it can be done
like this in a suspected case. If oral temperature is found to be more than
97.5*F, then the patient may be quarantined for further tests or may be
asked to rest for half an hour, give him tea and ask whether he is feeling
again exhausted. This small measure will easily detect infection and
the spread of further infection may be quickly stemmed. A true doctor is
never adamant, he is always ready to learn new things, because his priority
is only the welfare of his patients and nothing more.
Many years ago, I had successfully treated a case of vertigo, in which case
US doctors have failed to diagnose, despite conducting all kinds of tests by
keeping the patient in hospital for more than a week, because the patient’s
brother was himself a practicing doctor in US. This patient was a martial art
trainer. For this the US doctors had ignored to take an X’ray of his cervical
spine. Simply looking at the patient’s posture, I had come to the conclusion,
that this patient had cervical spondylosis, which had also affected his pulse,
because that was intermittent (though his ECG did not reveal anything).
Simply X’ray of cervical spine revealed that he had spondylosis,
and this patient was cured within three days by simply two medicines,
one was given for curing his spondylosis and another for correcting
his intermittent pulse. Plus he was also taught correct posture of sitting
and some yogic exercises and released.
What I want to prove here, doctors may miss out many small matters, which
may prove fatal or dangerous for the patient as well as for the people around
him, if he does not use his own instinct to treat. For this small negligence
the doctors had to regret later.
A few words on pneumonia:
Take all the three remedies mentioned under (H) taking them in
equal quantity in liquid form and mix them up in a sterilized bottle
and shake the bottle for two minutes and the mixture is ready for use.
In the event of suspected pneumonia, use this remedy pouring
five-drop in one teaspoonful of water for a dose one hourly. This
remedy is to be given simultaneously with remedies (A) and (B). Though
I wrote about this remedy, yet I do not think this remedy will be
required, if at the early stage itself remedies (A) and (B) are
administered. This remedy can be used, if pneumonia is suspected. But
still I can say pneumonia is rarest of the rare case if only
homeopathic remedies are used and other precautionary measures
mentioned below are strictly followed.
Two more remedies (I) Mephites3X and (J) Oxydendron Q have been
added for any emergency. If the cough is spasmodic, then along with
(A) and (B) but increasing the time gap of administration of (A) and (B),
(I)Mephites 3X in one drop a dose can be given four to five times
at an interval of say five minutes to arrest cough, this is only an
emergency medicine, both (A) and (B) as instructed above should
be continued until fully cured. In case if the patient develops dropsy
in lower extremities the (J) Oxydendron Q five drops can be added
with (C) Stigmata Maydis Q ten drops ( in half a cup of water) and
given to the patient orally as instructed about the dose related
to (C), say three times or as required.
But we have to deal separately with the patients with other complaints.
The WHO can consult me any time on my email for special
remedies for such patients. Diet will remain the same for all the
patients of corona virus.
Diet restriction is very important for recovery:
Avoid cold water, cold soup, exposure to outside cold etc. Give light
and easily digestible food; try to avoid animal products during
illness because it will not be assimilated properly in the system.
Avoid always both constipation and diarrhoea. Give plenty of warm
liquids to drink including fresh vegetable soup, plus light Horlicks
or Bournvita or D-protein, if the patient is diabetic or any other
nutritious liquid preparation can be given, but it must be light and
easily digestible. Later with slight improvement corn flakes with milk
or oats can be tried out. With gradual improvement the patient can
slowly switch over to normal diet. No eggs during illness have to be
given; it will harm the patient’s digestive system. This is important.
Fruits and Salads also have to be avoided even if there are slight
symptoms of colds and cough, for they will harm the patient. Instead
fresh lime juice in warm water is to be given several times a day.
Even avoid boiled green leafy vegetables during illness; any raw
vegetables are contra-indicated. About diet I have drawn information
from Ayurveda. Ayurveda insists on absolute diet restriction during
any illness, and I found this information extremely useful with my
patients during every kind of illness. I doubt on the aptitude of
modern dieticians, if they have got this knowledge of Ayurveda on
Homeopathic remedies, since they are harmless, can be
administered even at an interval of five minutes or early
to save a patient’s life according to severity, and later with
improvement time gap can be increased.
Some more precautionary measures:
To prevent the infection of runny nose to percolate down to the
lungs or lower respiratory tract, the throat of the patient should
always be covered with muffler and head with a cap and more and more
hot nutritious liquids such as Horlicks or Bournvita is to be given
again and again orally if patient is in a condition to sip.
Other precautionary measures may be continued as prescribed in
medical literature on infection. I think inadvertently some wrongs
are being committed by the doctors while treating the patients
of Corona Virus infection, that is why simple viral infection is
turning into pneumonia, otherwise there is no chance for any viral
infection, no matter the name, turning into pneumonia, according to
my experience if there is no serious earlier abnormality in the system
like diabetes, hypo-thyroid, AIDS, renal problem, TB infection,
auto-immune disease or the patient is under steroid for some illness
etc. or WBC count is less than 6800. These abnormal cases have to be
treated separately as I have stated above.
Kindly do not neglect my submissions, just analyse them
logically, because it relates to saving unnecessary loss of precious
human life because of ignorance. Please mind it, learning has no
limit. This battle against the demon Corona Virus has to be won under
all circumstances together. Moreover, I am also a researcher.
A few inadvertent mistakes committed by doctors:
1) Are the doctors making experiments with any antibiotics
on viral infection, though in viral infection no antibiotics will be
effective as we know?
2) Are the patients being kept in air conditioned room or simply
in a well-ventilated room?
3) Are the indoor patients being administered dextrose intravenously at
4) What remedies are being used to bring down fever? Are they
using paracetamol or any other anti-fever remedy to trigger sweating?
If the doctors are doing one or the other, then they are
committing grave blunder, which I feel is the root cause of
turning simple viral infection into pneumonia and triggering fatality,
though I think the duration of corona virus to die its own natural
death is not more than time taken by any other viral infections.
Same is the case with AIDS
virus, though which is much slower in its action, takes a pretty long
time to be negative. Corona and AIDS viruses highly mutate, it is
a known phenomenon with every other virus, and they are to be
tackled accordingly. Leave AIDS aside, I am coming to Corona.
Now think seriously what I am writing, because it is a matter of
saving the world, including China, from deadly Corona Virus infection.
If it is treated lackadaisically and whimsically by any medicines
experimentally, then it may prove fatal for the world very quickly.
Man is always helpless in front of Nature’s might.
1) Administration of antibiotics always triggers diarrhoea even in
normal person and also affects the functions of other organs including
liver which renders the body weak, and definitely the simple colds
becomes severe and percolates the infection down into the lungs due to
lowered immunity. Since no antibiotics is effective in any viral
infection, advise the doctors to refrain from using any antibiotics on
trial basis, if they are using at all, including AIDS medicines and steroids.
2) Since the patient himself is suffering from colds and prone to
catching cold, he should not be kept in any air conditioned room, even
if kept, the room temperature should not be more than 26*C, if
required better use fan. Virus may survive in air condition filter. It is
always wise to keep such patients in a well-ventilated room than
in any air-conditioned one or else the patient can be shifted to any
warmer region and kept only in well-ventilated room. This helps
the condition of the patient from getting further deteriorated.
Warmer region is always good to tackle any acute viral infection,
virus cannot tolerate heat above 30*C.
3) Avoid using dextrose to indoor patients (this is very
important), for this will further cool down the body, which is not
very good for patient’s health. Perhaps this fact is not known to
doctors, I apprehend. With administration of dextrose the sick body
will easily become prone to pneumonia. This is the main reason as to
why most of the terminally ill patients develop pneumonia in hospitals
and their death is hastened, perhaps this is the main cause for
most of the deaths in hospitals, though nobody has tried to find this out
so far, I feel. Dextrose has a special property to cool down the body
swiftly, therefore, it is liberally used in jaundice. Ayurveda says bile has
the property to heat the body; therefore to cool it down sugar cane
juice is prescribed in normal jaundice. In viral infection the body is
already infected with colds, and infusion of further colder things into the
blood is highly harmful. With infusion of dextrose the body will
invariably shifts colds into the lungs and pneumonia is triggered.
Rather depend on oral administration of liquids, if patient is not
unconscious, and if unconscious use ryles tube for feeding liquids or
the patient can be intravenously infused one bottle of plain sterile,
demineralised, distilled water followed by one bottle of sterilized
water with 3% sodium chloride or as convenient, and then finally a
bottle of ringer lactate (all in 500 ml quantity) because the patient
may experience low blood pressure during severe colds or as decided by
on duty doctors according to the condition of the patient, but no
dextrose has to be used under any situation, and simultaneously
some liquid nutrition may be given from time to time through ryles
tube if the patient is unable to feed himself. Any liquid given
intravenously must be of room temperature, otherwise it will deteriorate the
general condition of the patient further. Proper nursing is very important
for quick recovery. But vitamin supplements, including B-complex
to prevent the blood pressure from falling is very important for the patient,
because during severe colds and fever quickly minerals/vitamins are lost
from the body, and these have to be compensated through
intra-muscular injections of vitamin supplements.
Under no circumstances lasix is to be used as it will throw away
quickly nutrition from the body. Use of lasix in a patient with
compromised renal function will only hasten death instead of curing.
If the renal function of the patient is compromised simply use instead
(C) Stigmata Maydis Q in ten-drop a dose in half a cup of water twice
or thrice a day or more as per necessity (it is an excellent remedy to
promote diuresis), which will quickly restore normal renal function.
Stigmata Maydis Q is highly effective in anasarca also. I used this remedy
sometime in the past in acute nephritis with good result. If no
antibiotics or pain killer/anti-fever remedy like paracetamol or
medicine like lasix is administered, there is no question of
deterioration in renal function. Frequent use of lasix in patients
with urinary dysfunction, I feel, is the major cause of acute renal
failure in hospitals plus body is quickly rendered weak and the patient’s
general condition deteriorates. Please find out! I shared this finding with
the CDC also.
Most of the doctors commit similar and other mistakes in viral and
other infections and become the inadvertent cause of patient’s death.
Unfortunately a lay man is unaware of these facts, nor the doctors.
Even then if blood pressure for some reason falls or pulse rate falls
below 60, then start giving (G) Naja T 30 in one drop dose at an
interval of five minutes orally. After administration of simply three
to four doses, the blood pressure will begin to rise to normal level
including the pulse rate and patient will open eyes, if unconscious,
you don’t need adrenaline. There is no comparison of this homeopathic
remedy in restoring the compromised heart function with any
other remedies in the world of medicine; very simple, but highly
effective. This is an excellent remedy for serious bradycardia also,
no matter the name. Just try out yourself and see!
Naja T 30 is a great heart saviour. It can be used in OT also
from time to time, if for some reason the patient’s life is threatened
due to falling blood pressure. Using this remedy, I can claim with
authority I saved many patients from imminent heart failure including
the life of some doctors. Just use it, and, I think, it is far superior
to adrenaline in restoring failing heart function. If the patient is
unconscious, then slightly open his mouth with the help of a spoon
and just drop a drop of Naja T 30 on his tongue, every two to five
minutes and see the miracle yourself. His blood pressure is bound
to rise quickly in no time. Knowledge is not a slave of any expert.
4) No paracetamol or anti fever medicine is to be given, which
triggers vigorous sweating in the patient, because these medicines
simply cool down the body abnormally but do not treat. Moreover, the
air-conditioned room’s cool temperature further impacts adversely on
the ailing body. In any infection, the body’s defence mechanism is
always weak, and a sudden fall in body’s temperature quickly transfers the
infection into lungs and pneumonia sets in, which triggers bacterial
infection later, I feel, otherwise there is no question of getting pneumonia
in simple viral infection, which is supposed to go away on its own by
taking homeopathic remedies suggested by me above within two to three
days, though it is always wise to continue the medicines until fully
cured. Though the effect of corona virus is aggressive, it is not
incurable. Who has first started the COVID-19 or how it has emerged,
leave all these controversies under wraps for the time being until we
successfully eliminate this disease from the world.
Do not be afraid if the fever rises even up to 104*F, with
administration of (A) and (B) mixture, gradually temperature will be
bound to come down or simple cold compress may be used on forehead,
and (C) also helps in normalizing the temperature. This situation will
not arise, if with slight feeling of illness, (A) and (B) are
administered to the patient as instructed quickly. If any serious
patient is unable to take the medicines on his own, just open his
mouth with the help of a spoon and pour the medicine (A) and (B), one
drop instead of five drops every three/five minutes on his tongue
alternately until he opens his mouth on his own and becomes conscious,
then in a normal way medicines have to be administered as instructed
Please go seriously into my suggestions, I feel the many
doctors are certainly committing one or other blunder as I pointed out
above while treating the patients due to their inexperience in these
tiny but serious matters, otherwise why there is so many fatalities.
If my advice is followed seriously then Corona Virus infection can be
eliminated within a few days not only from China, but from the world,
I am fully convinced about my mode of treatment, but no allopathic
remedies have to be tried, use only homeopathic remedies suggested by
me, and see the miracle. Just don’t neglect what I have stated, we have to
save human life from perishing, which is not a joke, nor am I cracking
any joke or making false tall claims. They are all based on my personal
experience gained over years of free practice..
Random use of allopathic remedies simultaneously for experiment
will simply spoil the treatment procedure and the condition of the
patient will deteriorate and people will start blaming homeopathy that
it had harmed. Mind it, homeopathic medicines have no side effects,
but their effect is wonderful, unless used no one will believe their
efficacy. It is faster to treat any patient in homeopathy than in any
other systems of medicines in the world, surgery is different, it is
A great doctor is he, who does not follow blindly the
instructions given in any medical text book and rather uses his own
intelligence and keeps his mind receptive and open always,
because every patient is an individual, therefore has to
be treated accordingly. It should always be kept in mind, nobody is
perfect except God, and knowledge is limitless and every system
of medicine has its flaws. In my opinion corona virus is not that serious,
though it may be more virulent so what, it has assumed this form
because of commission of some mistakes either inadvertently or due
to inexperience in treatment procedure by doctors, a few of them
I have pointed out above. A doctor should always keep in mind,
he is not the actual healer, he only treats, but healer is only God.
When there is no relief from any side, the affected countries
may kindly be instructed to follow the above prescription and see the
miracle, loss of human life with corona virus infection will
abruptly stop and patients will also recover fast. I am convinced
about the effectiveness of my remedies. I acquired this confidence by
treating hundreds of patients successfully free of cost for more
than thirty years, even in many cases given medicines from my pocket.
Yes, the medicines procured must be obtained in sealed bottles and
genuine, otherwise they will not work.
Wuhan in China is a cold region, and doctors are fighting viral
infection, which is mainly associated with cold symptoms, therefore, I
feel if corona virus patients could be transferred to warmer regions,
the recovery will be fast, though it is for the local government to
decide according to its convenience.
May God bless! There is nothing to worry, have confidence and
I am with everybody no matter the country. Treatment is to be
conducted systematically as I have suggested above, nothing is to be
attempted haphazardly, because it relates to saving a human life. One
whimsical attempt brings a chain of destruction, please allow no more
experiments with human life, when there is nothing in hand with any
experimenter worthy of any help to corona virus patients.
I have made many additions in the list of medicines from one letter
to another, as I noticed emergence of new symptoms in corona virus
May God bless mankind! Have confidence and don’t worry! I know
my theory is not acceptable and may sound out of the context, but my
humble submission to them to look into my suggestion, when the hands
of others are empty, I am at least giving some ray of hope. I was deeply
moved by the tears of the President of Italy, his tears clearly show that
despite his genuine desire to stop the loss of innocent life of his citizens,
he is helpless. Two more remedies I may add: when the patient
faces extreme distress due to his inability to breathe, and the patient is
required to be put under ventilator. This situation as I have learnt is similar
to the attack of asthma, then 1) Blatta Orientalis Q and 2) Passiflora
Incarnata Q can be tried out. Pour in a half cup of water 1) Blatta forty thirty
drops and 2) Passiflora sixty drops and give to the patient orally one teaspoon-
ful of remedy at a time at an interval of ten minutes. With two to three doses
the patient will feel absolutely relieved. This will work, when the cough is
dry and breathing extremely stressful. It is advised I) Mephites 3X one to
two doses can also be administered simultaneously, if required, during
the time gap. Otherwise when cough is productive and non-stoppable,
then mixture of Lemana Minor 200 and Kalibichromicum 200 in one drop
a dose at an interval of half an hour will relieve the symptoms. When
production of phlegm stops then simultaneously the medicine can also
But to obtain full relief the precautions given under diet and nursing and ‘
cautions given to the attending doctor have to be strictly followed. As per
my experience, no viral infection, including corona, will pass into lungs, if some
precautionary measures are taken and simultaneously immunity is also raised.
When nothing in hand just try out remedies (homeopathic) suggested by me
in one or two patients and observe. There is always a ray of hope, we are a
only the medium of Great Invisible Power, who is called God, because He is the
I appreciate the good information. One thing I disagree with is your idea that Rush said the virus is a bio weapon. He clearly said the Chinese weaponized the virus against us, not that it was a bio weapon. After it got started, they used it against us to harm our economy and our president. Weaponizing something doesn’t, at all, mean it’s a bio weapon.