Women's Hormones & Natural Anti Aging | Special Report

Date: 10/01/1997    Written by: Jon Barron

Progesterone Creme & Hormonal Balancing

Every woman between the ages of 13 and 117 needs to seriously consider supplementation with a natural progesterone creme.

Why? Because virtually every woman who lives in an industrialized country (the United States, in particular) is at high risk of estrogen dominance because of exposure to xenoestrogens. Xeno- estrogens, which are mostly petroleum based synthetic estrogens, are now present in massive amounts in our food chain, water supply, and environment.

At one time, our diets afforded some protection. Fruits and grains and vegetables (in their natural state) provide low-action phytoestrogens for the body. These low-action estrogens fill the body's estrogen receptor sites -- making them unavailable for use by the more potent estrogens -- both natural and synthetic. Unfortunately, today's diets are dominated by processed foods, which are stripped of these beneficial phytoestrogens. The net result is that virtually all of the body's receptor sites are ready and waiting for the far more intense estrogens.

Some high potency estrogens (such as estrone and estradiol) are produced by the body itself. But far and away, the greatest problem comes from the powerful and destructive petrochemical-based xenoestrogens. Not only are these xenoestrogens omnipresent, they are considerably more potent than estrogen made by the ovaries -- some even potent in amounts as small as a billionth of a gram.

Before we proceed, it is important to understand what role estrogen plays in the body. In addition to promoting the growth of female characteristics at puberty, the estrogen hormones also promote cell growth. It is the estrogens, for example, that stimulate the buildup of tissue and blood in the uterus at the start of the menstrual cycle. The problem comes when high levels of estrogen (natural and synthetic) are unopposed by sufficient amounts of natural progesterone, which leads to continuous, unrestrained cell stimulation. Problems that can occur include:

  • Excess estrogen is the only known cause of endometrial cancer
  • Increased risk of breast cancer
  • Loss of bone mass
  • Increased risk of autoimmune disorders such as lupus
  • Fibrocystic breasts
  • Fibroid tumors
  • Depression and irritability
  • PMS symptoms such as cramping and bloating -- in addition to depression and irritability
  • Menopausal symptoms such as hot flashes and night sweats -- again, in addition to depression and irritability
  • Decreased sex drive
  • Increased body hair and thinning of scalp hair
  • Migraine headaches
  • Impaired thyroid function, including Grave's disease
  • Increased body fat
  • Increased blood clotting
  • Impaired blood sugar control
  • The astounding acceleration of puberty in young girls from an average age of 14 to 15, to now as young as 9 or 10. (This represents a speed up of as much as 1/3 sooner in their lives and has frightening implications for long term health.)
  • And, finally, xenoestrogens have been strongly implicated in declining male sperm production and the increase in the rates of testicular cancer and prostate cancer

The Answer: Balance Estrogen

The only natural balancer to excessive estrogen in the body is natural progesterone -- not more estrogen. But what about the synthetic "progesterones" (such as Provera) that your doctor recommends? Progesterone is a natural substance, and as such cannot be patented. The pharmaceutical companies, therefore, have to modify it slightly. They literally create a new molecule, called medroxyprogesterone -- that does not exist in nature -- in order to take out a patent. This "slightly" modified artificial progesterone is what most doctors prescribe. What effect does slight modification have?

Consider the fact that the testosterone molecule and the estrone molecule are virtually identical -- except for the fact that the positions of the oxygen atom and the OH atoms change places. This slight "modification," however, happens to be enough so that one hormone makes men...and the other women.




Even closer is the similarity between DHEA and estrone. The molecules are actually identical except for the location of some of the double bonds between carbon atoms. You cannot get closer. And yet the function of DHEA and estrone could not be more different.

And now look at the difference between natural progesterone and Provera:



The bottom line is that Provera is not natural. It's a synthetic form of progesterone that carries a whole range of serious side effects. A small sampling of these side effects, as listed in the Physician's Desk Reference, includes:

  • Depression
  • Birth defects
  • Increased body hair
  • Acne
  • Risk of embolism
  • Decreased glucose tolerance
  • And allergic reactions

Now, in exchange for these significant side effects, Provera does offer some protection against endometrial cancer and a very modest increase in bone formation.

On the other hand, supplementation with natural progesterone has NO known side effects. It is best utilized by the body when administered transdermally with a skin creme that contains approximately 500 milligrams per ounce of natural progesterone and offers the following potential health benefits

According to Dr. John R. Lee, the author of What Your Doctor May Not Tell You About Menopause, natural progesterone may significantly improve bone formation -- by as much as 15% - 35%. (Understand, this is unique to natural progesterone. Estrogen supplementation does not increase bone formation; it merely slows the rate of loss for a 5-year period around the time of menopause. And man-made progestin only mildly increases bone formation. If you are worried about osteoporosis, there is only one substance known that significantly improves bone formation -- and that's natural progesterone.)

  • Increased progesterone levels in the body may help to protect against endometrial cancer
  • They may also help protect against breast cancer
  • In addition, supplementation with natural progesterone can help relieve symptoms of PMS
  • Relieve symptoms of menopause
  • Normalize libido
  • Improve the body fat profile
  • Improve sleep patterns
  • And help relieve migraine headaches

The bottom line is that every woman living in the industrialized world should seriously consider supplementation with natural progesterone.

  • If you decide to begin a regimen of natural progesterone supplementation, look for a premium quality balancing creme that contains a minimum of 500 milligrams per ounce (the amount recommended by Dr. Lee) of 100% pure, USP grade progesterone, naturally derived from either wild yam or soybeans. Look for a natural vegetarian formula that uses no artificial or synthetically derived fragrances, parabens or preservatives. Look for a formula that uses all natural oils and an enhanced liposome delivery system to help move the progesterone through the skin. And finally, look for a formula that uses organic wild yam…if you can find it. It’s getting harder and harder to find companies that use it.

Whether you're still going through your menstrual cycles (or whether you're pre-menopausal, or menopausal, or post-menopausal), you need to seriously consider supplementation. The benefits are extraordinary; the risks virtually non-existent. And the risks of not supplementing potentially include: an increased risk of breast cancer, endometrial cancer, and osteoporosis -- to reiterate just a few. (And for men, natural progesterone can help with depression and can help relieve prostate problems.)

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    Submitted by Guest on
    July 13, 2011 - 1:00am

    Dr. Mercola wrote an article which says natural progesterone cream builds up in bodyfat tissue over time and after a period of time, the cream stops working. I assume the more bodyfat a woman has, the greater the problem will become. Here is the link to his article http://www.mercola.com/article/progesterone/cream.htm In another article by Dr. Mercola, he says "Sublingual[Progesterone] drops offer the best of both worlds, as it enters your blood stream directly and will not build up in your tissues like the cream can..." http://articles.mercola.com/sites/articles/archive/2009/12/26/This-Natural-Hormone-Can-Help-Heal-Your-Brain-Injury.aspx I'd sincerely appreciate a response to this, as I've noticed you've replied to articles written by Dr. Mercola in the past.

    Submitted by BaselineFoundation on
    July 13, 2011 - 8:54pm

    The advantage of drops is that they reach the bloodstream more quickly with a cream. The disadvantage of drops is that they reach the bloodstream all at once, causing spikes in your progesterone levels, whereas the progesterone in a transdermal cream is measured out into the bloodstream in a more continual – even basis. As to it not working if it builds up in the fat tissue, that’s not correct. It means that you won’t absorb any more into your fat cells when applied transdermally…until, that is, the progesterone already in your fat cells makes its way into your bloodstream. In effect, it’s a self-regulating system.

    Submitted by Vivian Riggan on
    March 5, 2016 - 10:10pm
    Houston , Texas

    I have had lots of experience with hormones, I just turned 74 on Dec. 8,2015 and I stared on Estradiol, and prometrium
    Both are made from soy and yams, prescription only
    They are estrogen and progesterone and I started at the age of 45 and that is going to soon be 30 years, I go to the Gym at least 5 days a week and eat mostly vegetable's organic, and occasional fish, chicken, only grass beef occasionally
    I feel great, and constantly am being told I look 45 and even younger
    If you want lasting results, oral by mouth works, and I have tried the over the counter creams and they work okay at first, maybe about 3 months
    Also I have tried the creams by compounding pharmacies and the same thing , after a few months they do not work any more, and I am telling all women if you want look much younger feel great, have beautiful skin, go by mouth , that works as I have been doing this a long time
    I look good, I look Young and I will take my hormones forever

    Think about it, when you are young you have all your hormones and hardly hear of younger women getting breast cancer, because they have all there hormones, as you get older your skin starts to sag and you start aging and your neck is sagging and you are not walking strong and tall, and have the confidence you had when you looked good and your skin was tight
    Every one ask me what is your secret
    I tell them, hormones, organic diet, at least 64 ounces a day of water
    Exercise, strength training walk an hour a day
    Estrogen Protects women, that is why we live longer than men and it protects your heart
    I take about 25 or more supplements a day
    I could say a lot more but for now enough
    The hard part is getting your dose just right
    start out low, as 0.5 estradiol, and 100 mg of Name brand Progesterone
    You will have to convince your doctor for a prescription, because they are so scared of breast cancer, and then you would have to find a doctor that specializes in hormones
    The estradiol and progesterone protects you from cancer and so many other benefits, do some research on your own
    That Nurse's study, was a flawed study for the hormones,
    as it was done with Provera, synthetic progesterone
    and the estrogen was done with Premarin, made from pregnant mares urine



    Submitted by cecilia on
    July 18, 2011 - 7:58am

    Hi there

    could Progesterone Creme benefit my daughter who is 20 years old with grave disease, if yes, what is the instruction to use?

    thank you

    Submitted by Guest on
    August 3, 2011 - 11:00am

    Can you please recommend a brand that entails all that you suggest we look for?

    Many thanks,

    Submitted by BaselineFoundation on
    August 3, 2011 - 4:48pm

    Just click on "Products" above and see our list of recommended products and where you can buy!

    Submitted by ATHENA on
    November 3, 2014 - 12:29pm
    Anaheim , California

    Where can I buy this product hormonal-balancing-progesterone creme
    The creme

    Submitted by BaselineFoundation on
    November 6, 2014 - 10:49am

    See my reply to the same question above. 

    Submitted by Kerry Blankenship, Regional Vice President on
    November 28, 2011 - 5:59am

    Arbonne is a health and wellness company with 31 years of being
    plant based and Vegan Certified. The FDA does not regulate anyones
    skin care or wellness products - not even ours; however, Vegan Certification is huge and a fabulous "watch dog" to guarantee not
    only do we not test on animals but we have NO animal by-products - ie
    lanolin (from sheep).
    Our phyto-prolief is what is discribed in this article...only $34 in a
    pump container...very impressive. Please contact me.

    Kerry Blankenship, Regional Vice President
    Arbonne International

    Submitted by Mike Maskery on
    August 4, 2011 - 2:45am

    Is it possible to use progesterone after having breast cancer Mike

    Submitted by BaselineFoundation on
    August 8, 2011 - 4:41pm

    It depends on the type of breast cancer. Is it estrogen or progesterone driven? In either case, you would want to check with the oncologist.

    Submitted by Demeter on
    November 8, 2011 - 1:52pm

    2 questions: Where in the body should be applied? and will it help to hair loss?

    Submitted by BaselineFoundation on
    November 11, 2011 - 1:54pm

    Hi Demeter, Depending on the product you use, I would just check the manufacturer's instructions on where to apply the cream.  

    Submitted by Kathy on
    December 14, 2011 - 4:13am

    Have you seen cases where balancing creams have been used on pre-teen girls as young as 10?

    Submitted by BaselineFoundation on
    December 16, 2011 - 11:18am

    Yes we have, but we would recommend that it only be done with the permission and guidance of the girl’s pediatrician.

    Submitted by gray on
    November 26, 2012 - 2:07pm

    What happened when you gave your 10 yr old the bal cream? My 10 yr old had her 1st period for 2 wks now.

    Submitted by Candice on
    February 19, 2012 - 10:22pm

    Is progesterone cream (or drops) safe for nursing mothers?

    Submitted by BaselineFoundation on
    February 20, 2012 - 6:21pm

    For obvious legal reasons, we cannot diagnose or prescribe for specific conditions – merely provide information. Check with your physician. You might also find this newsletter useful. http://www.jonbarron.org/detox/dietary-supplements-preconception-pregnancy-post-partum

    Submitted by Kim Rader on
    November 14, 2012 - 8:15am

    I have been enjoying the natural progesterone in Progessence Plus Serum, an essential oil mix of P4 with DHEA and other essential oils. I'm curious if you have any experience with this product or feedback?

    Submitted by Jenny Janssen on
    November 14, 2012 - 10:41am

    Is the generic version of Estrace, Estradiol safe?
    Does one need a prescription for Natural Progeserone?

    Submitted by Erin on
    November 16, 2012 - 1:53am

    Jon, I have a friend who is TS (transsexual-MaleToFemale) that use HRT to transition. Does this affect them as it does genetic females?

    Submitted by Jenny on
    April 15, 2013 - 4:29am

    I want cure ovarian cyst and my balance my hormone.

    Submitted by April koning on
    November 9, 2013 - 7:48pm

    Is this progesterone cream 'bio-identical'?

    Submitted by Sonia on
    November 9, 2013 - 9:44pm

    My little girl is not quite 4 with suspected estrogen dominance. Have children this young ever used progesterone cream before?

    Submitted by BaselineFoundation on
    November 11, 2013 - 8:41pm

    Yes we have seen this before, but we would recommend that it only be done with the permission and guidance of the girl’s pediatrician.

    Submitted by Cristina on
    July 22, 2014 - 11:41am

    Hello I am 17 and have excessive hair and dandruff and excessive acne my doctor just put me on birth control pills and thats it and the hair is worse as well as acne is progesterone cream good for girls with pcos? will it help ? please answer and ThankYou

    Submitted by BaselineFoundation on
    July 23, 2014 - 4:25pm

    You might want to check out this newsletter in which Jon discusses PCOS about 1/3 of the way into it. http://jonbarron.org/article/supplements-preconception#.U9Ax6NEnKbg

    Submitted by JD on
    September 3, 2014 - 6:26pm

    one truly needs a full blood workup before introducing hormones into one's body. Just taking "progesterone" without knowing how much is required by your own body is foolish. Improper balance of hormones introduced into the body can have detrimental effects including suggestion to breast cancer or stroke. Always wise to know if you body needs it before you add something. this goes for all supplementation as well. Cleansing is a wonderful idea and I subscribe to that. I am cautious of taking handfuls of "pills" until I see where my bloodwork stands.

    Submitted by BaselineFoundation on
    September 7, 2014 - 2:35pm

    Yes, testing is certainly good, but:

    No one is recommending that you take hormone “pills.” The recommendation is that you use a topical crème containing natural progesterone that is absorbed into the fat cells underlying your skin, from where it is slowly released into your bloodstream.

    Also, do you eat any soy beans or soy-based food products? They are high in phytoestrogens. Incidentally, phytoestrogens are also found in other legumes, namely kidney beans, chickpeas, peas, lentils and peanuts. Additionally, isoflavone phytoestrogens can be found in food sources such as wheat bran, barley, red cabbage, broccoli, black and green tea and the herb red clover. Do you eat any of those? To be consistent, you would want to test your hormone levels before eating any of these foods too. And I’m not even going to mention conventionally raised animal or dairy products or unfiltered water, as I’m guess you don’t consume those. But for those who do, they are also high sources of chemical estrogens.

    Testing is certainly good. But to put it simply, our environment has been loaded with chemical estrogens. The vast majority of people on the planet are more likely to suffer from exposure to chemical estrogens than be hormonally balanced. 

    Testing is good. But if you don’t test, natural progesterone crème is probably a good bet.

    Submitted by Pamela Lubina on
    February 20, 2017 - 1:09pm
    HIbbina , Minnesota

    If i am taking womens formula do i need a progesterone cream?


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